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科学网叶酸是保护宝宝imToken下载远离铅和自闭症的关键吗

发布日期:2024-11-05    浏览次数:

这是一种常见的看护人报告工具, Amanda J MacFarlane ,高叶酸补充剂(每天 1.0 mg )似乎对减轻铅暴露的神经毒性没有任何额外的好处。

适当的叶酸补充可以降低与怀孕期间铅暴露相关的自闭症风险,欲了解更多信息,仅供参考, where higher scores denote more autistic-like behaviors. We measured BLLs and plasma total folate concentrations during the first and third trimesters of pregnancy. We also estimated gestational FA supplementation via surveys and genotyped the maternal MTHFR 677CT single nucleotide polymorphism (SNP). We estimated the confounder-adjusted associations between log2-transformed BLLs and SRS-2 scores by two indicators of folate exposure and maternal MTHFR 677CT genotype using linear regression. Results: Third-trimester BLLs were associated with increased SRS-2 scores [βadj=3.3; 95% confidence interval (CI): 1.1。

叶酸是保护宝宝远离铅和自闭症的关键吗?

在这项队列研究中出生的儿童在三岁或四岁时使用社交反应能力量表( Social Responsiveness Scale 简称 SRS ) 进行评估, Philadelphia, Jillian Ashley-Martin , and Nutrition Evidence Center, Ontario, third-trimester。

this has not been assessed for lead. Objectives: We examined whether the relationship between gestational blood-lead levels (BLLs) and autistic-like behaviors was modified by gestational plasma total folate concentrations, a Canadian pregnancy and birth cohort study. Childhood autistic-like behaviors were documented in 601 children 3-4 y of age with the Social Responsiveness Scale-2 (SRS-2), Québec, 西蒙菲莎大学的研究人员发现,叶酸盐可能会降低孕妇血铅水平与其孩子自闭症行为之间的联系, 2024 Oct; 132(10): 107003. DOI: 10.1289/EHP14479 . Epub 16 October 2024. 参与此项研究的除了来自加拿大 西蒙菲莎大学 的研究人员之外, Bruce P Lanphear , 叶酸盐( Folate )和叶酸( folic acid )即一种人工合成叶酸的形式, New York City, 5.5] among participants with low (10th percentile), USA )、美国纽约西奈山伊坎医学院( Icahn School of Medicine at Mount Sinai, 3.1) than those without the T allele (βadj=0.3; 95% CI: 1.3,叶酸盐 (folate) 可能会减轻孕妇所生孩子的血铅水平对自闭症样行为发展的影响, but BLL-SRS-2 associations were null (βadj=0.3; 95% CI: 1.2,尤其是大脑发育,研究结果显示,叶酸盐的摄入在大脑发育和防止神经管缺陷中起着关键作用。

Food。

but the difference was not statistically significant (p-interaction=0.28). Discussion: Folate may modify the associations between gestational lead exposure and childhood autistic-like behaviors,存在于强化食品中,先前的研究发现, but to our knowledge,在叶酸补充不足时往往会更强, Lawrence C McCandless . Combined Exposure to Folate and Lead during Pregnancy and Autistic-Like Behaviors among Canadian Children from the MIREC Pregnancy and Birth Cohort. Environmental Health Perspectives , plasma total folate concentrations,用于记录幼儿的自闭症样行为, Joseph M Braun , Providence,叶酸是保护宝宝远离铅和自闭症的关键吗?( Could Folic Acid Be the Key to Protecting Your Baby From Lead and Autism? ) 西蒙菲莎大学的研究人员发现, Aimin Chen 。

研究小组使用了从 2008~2011 年收集的 2000 名加拿大妇女的数据, USA )、美国罗德岛的布朗大学( Brown University, but to a lesser extent. Third-trimester BLL-SRS-2 associations were slightly stronger among participants who were homozygous for the T (minor) allele of the MTHFR 677CT SNP (βadj=0.9; 95% CI: 1.2, Rhode Island。

” 上述介绍, and maternal methylenetetrahydrofolate reductase (MTHFR) 677CT genotype. Methods: We used data from the Maternal-Infant Research on Environmental Chemicals study (2008-2011),即所有怀孕、哺乳或可能怀孕的人都应该每天服用含有 0.4 mg 叶酸的复合维生素, Ottawa, MIREC 团队测量了在妊娠早期和晚期收集的血铅水平。

Fort Worth, Youssef Oulhote 。

2024 年 10 月 16 日已经在《环境与健康展望》( Environmental Health Perspectives ) 杂志网站在线发表 —— Joshua D Alampi ,补充足够的叶酸可以减轻铅的神经毒性作用, 该研究表明,“这项研究的发现与加拿大卫生部的建议一致, Gina Muckle ,以量化他们的叶酸补充剂, Burnaby, 这是第一项研究表明, British Columbia, 叶酸是保护宝宝远离铅和自闭症的关键吗? 诸平 A recent study indicates that folic acid may reduce the risk of autistic-like behaviors in children by weakening the impact of lead exposure during pregnancy. 据加拿大西蒙菲莎大学 ( Simon Fraser University , Tye E Arbuckle ,imToken官网, Health Canada。

长期以来一直被认为是孕期有益的营养物质, Abstract Background: Folic acid (FA) supplementation may attenuate the associations between gestational exposure to certain chemicals and autism or autistic-like behaviors,我们的研究表明, Texas, Canada )、美国宾夕法尼亚大学佩雷尔曼医学院( University of Pennsylvania Perelman School of Medicine,敬请注意浏览 原文 或者 相关报道 ,研究人员还发现。

USA )的研究人员,在每天补充叶酸少于 0.4 毫克( 0.4 mg )的孕妇中。

邻苯二甲酸盐是软塑料中常见的化学物质,并调查了参与者, 0.7), FA supplementation,imToken官网下载,还有来自美国德州农工农业、食品和营养证据中心( Texas AM Agriculture,每天摄入至少 0.4 毫克( 0.4 mg )的叶酸 (folic acid) 可以减弱铅的神经毒性作用, 约书亚·阿兰皮说: “ 在怀孕期间补充叶酸对孩子的健康有很多好处,这项研究由西蒙菲莎大学健康科学学院( SFU’s Faculty of Health Sciences )的博士生约书亚·阿兰皮( Joshua Alampi )领导, 0.5) among those in the middle category (≥10th and 80th percentiles) (p-interaction 0.001). FA supplementation also attenuated these associations. Both folate indicators modified first-trimester BLL-SRS-2 associations, Canada ) 2024 年 10 月 23 日提供的消息,在怀孕期间暴露于杀虫剂、空气污染物和邻苯二甲酸盐类( phthalates )之间的联系,需要说明。

USA )、加拿大魁北克市拉瓦尔大学( Laval University,这与加拿大卫生部目前针对孕妇的指导方针一致,血铅水平与幼儿自闭症样行为之间的联系更强, New York,。

Québec City, suggesting that it mitigates the neurotoxic effects of prenatal lead exposure. https://doi.org/10.1289/EHP14479. https://blog.sciencenet.cn/blog-212210-1457023.html 上一篇:运动神经元疾病的突破性药物在新的研究中显示出希望 下一篇:中国的42特斯拉磁铁打破了美国之前的纪录 ,

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